Cosmetic products are used daily on a global scale. Therefore, it is necessary to ensure that these products, and their ingredients, do not cause any adverse human health effects under normal usage; to ensure this, risk assessment must be performed. Traditionally, risk assessments are performed in vivo, i.e. conducting tests on animals using the chemical(s) of interest. However, over the past decade there has been an increase in research into the use of alternative toxicity testing methods, such as in vitro, in chemico and in silico. Whilst there are a number of alternative techniques that may be employed, no one method can be used in isolation as a full replacement for an in vivo test.